MyBioSource.com's LOXL3 Antibody (C-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The LOXL3 Antibody (C-term) was generated using LOXL3, and lysyl oxidase like 3 as the antigen and it reacts with Human.
Description
This gene encodes a member of the lysyl oxidase gene
family. The prototypic member of the family is essential to the
biogenesis of connective tissue, encoding an extracellular
copper-dependent amine oxidase that catalyses the first step in the
formation of crosslinks in collagens and elastin. A highly
conserved amino acid sequence at the C-terminus end appears to be
sufficient for amine oxidase activity, suggesting that each family
member may retain this function. The N-terminus is poorly conserved
and may impart additional roles in developmental regulation,
senescence, tumor suppression, cell growth control, and chemotaxis
to each member of the family. Alternatively spliced transcript
variants of this gene have been reported but their full-length
nature has not been determined